Flavonoids and Tannins from Anogeissus latifolia

Document Type : Original research articles

Authors

1 Department of Pharmacognosy, Faculty of Pharmacy (Girls), Al-Azhar University, P.O. Box 11651, Nasr City, Cairo, Egypt.

2 Tanning Materials and Leather Technology Department, Chemical Industries Research Institute, National Research Centre, 33 El-Bohouth St. (Former El-Tahrir St.), Dokki, Cairo 12622, Egypt

Abstract

Anogeissus latifolia (Roxb. ex DC), Family Combretaceae, is considered as one of the most useful trees in India as the main source of the commercial Indian gum, known as ghatti gum and used for tanning processes. In traditional medicine it is reported for the treatment of many diseases like UTI infections, cardiac disorder and liver complaints and proved to have a wide range of biological activities due to its high content of tannins, appreciable quantities of flavonoids, terpenes and saponins.Two dimensional paper chromatography investigation of the 70% aqueous methanol leaf extract revealed the presence of high polyphenolic contents of versatile structures. This study describes the chromatographic isolation and identification of four flavonoids and three tannins metabolites for the first time from the leaf and stem methanol-soluble portions. Their structures were established as vitexin, isovitexin, isoorientin, orientin, gallagic acid bilactone (terminalin), puncalin and 2-O-galloylpunicalin based on the chromatographic properties, spectroscopic analyses (1H and 13C NMR) and HRESI-MS.

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